Experiment No 10 : The Observing effect of acetylcholine on isolated rectus abdominus of muscle of a frog.


d pharma 2nd year experiments
experiment no 10

Questions

1 What is the effect of acetylcholine on rectus abdominus muscle of a frog?

2. What is the mechanism of action of acetylcholine?

3 How the metabolism of acetylcholine takes place?

4 How the duration of action of acetylcholine is increased?

 5 Write to which category the rectus abdominus muscle belongs?

6 Write the names of the muscles other than rectus abdominus

7 Draw the graph (dose response) of effect of acetylcholine on rectus a frog

8 List five drugs, which causes contraction of skeletal muscles

9 What is the purpose of giving washings to the muscle preparation?

10 Write the 5 min. time cycle, which should be followed while performing the experiment.

 

Answers

Q 1 Ans Rectus Abdomins  muscle of the frog is the voluntary skeletal muscle that produces a lover contraction in response to the drug acetylcholine

 

Q .2Ans Acetylcholine in the serum exerts a direct effect on vascular tone by binding to muscarinic

receptors present on vascular endotheliom. These ceus respond by increasing production of nitric oxide.

 

Q . 3 Ans The Acetylcholine metabolism back into Acetate &  choline synaptic acetylcholinesterase breaks it back down into acetate, anions & choline .

 

Q.5 And The rectus abdominis muscle also known as the abdominal muscle rectus abdominal belongs to the anteriore abdominal muscles together with pyramidalis nerve .